| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 5 |
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| Ligand | BDBM50400789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_879200 (CHEMBL2208513) |
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| IC50 | 39.7±n/a nM |
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| Citation |  Armour, DR; de Groot, MJ; Price, DA; Stammen, BL; Wood, A; Perros, M; Burt, C The discovery of tropane-derived CCR5 receptor antagonists. Chem Biol Drug Des67:305-8 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 5 |
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| Name: | C-C chemokine receptor type 5 |
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| Synonyms: | C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40540.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51681 |
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| Residue: | 352 |
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| Sequence: | MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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| BDBM50400789 |
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| n/a |
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| Name | BDBM50400789 |
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| Synonyms: | CHEMBL2203621 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N4O2 |
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| Mol. Mass. | 472.6217 |
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| SMILES | Cc1nc2ccccc2n1[C@@H]1C[C@@H]2COC[C@H](C1)N2CC[C@H](NC(=O)C1CCC1)c1ccccc1 |r,TLB:19:18:14.13.15:11.17.10| |
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| Structure | 
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