| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 1 |
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| Ligand | BDBM50401556 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_882641 (CHEMBL2213078) |
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| Ki | 2511.89±n/a nM |
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| Citation |  Smethurst, CA; Bevan, N; Brooks, C; Emmons, A; Gough, PJ; Mookherjee, C; Moores, K; Peace, S; Philp, J; Piercy, V; Watson, SP; Zippoli, M In vivo activity of an azole series of CCR2 antagonists. Bioorg Med Chem Lett22:7252-5 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 1 |
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| Name: | C-C chemokine receptor type 1 |
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| Synonyms: | C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41180.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32246 |
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| Residue: | 355 |
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| Sequence: | METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLV
QYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTH
HTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRL
IFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVI
YAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
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| BDBM50401556 |
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| n/a |
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| Name | BDBM50401556 |
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| Synonyms: | CHEMBL2207091 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12ClF3N4O2S |
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| Mol. Mass. | 416.805 |
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| SMILES | FC(F)(F)c1cccc(c1)S(=O)(=O)Nc1cc(Cl)ccc1Cn1ccnn1 |
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| Structure | 
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