| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
|---|
| Ligand | BDBM50279106 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_884831 (CHEMBL2216585) |
|---|
| IC50 | 2±n/a nM |
|---|
| Citation |  Nguyen, W; Howard, BL; Jenkins, DP; Wulff, H; Thompson, PE; Manallack, DT Structure-activity relationship exploration of Kv1.3 blockers based on diphenoxylate. Bioorg Med Chem Lett22:7106-9 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily A member 3 |
|---|
| Name: | Potassium voltage-gated channel subfamily A member 3 |
|---|
| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 63835.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1513935 |
|---|
| Residue: | 575 |
|---|
| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
|
|
|
|---|
| BDBM50279106 |
|---|
| n/a |
|---|
| Name | BDBM50279106 |
|---|
| Synonyms: | 4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | 5-(4-phenoxybutoxy)psoralen | CHEMBL444449 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H18O5 |
|---|
| Mol. Mass. | 350.3646 |
|---|
| SMILES | O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
