| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Ligand | BDBM50044878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_204899 |
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| IC50 | 32±n/a nM |
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| Citation |  Wikel, JH; Bemis, KG; Audia, JE; McQuaid, LA; Jones, CD; Pennington, PA; Lawhorn, DE; Hirsch, KR; Stamm, NB QSAR study of benzoquinolinones as inhibitors of human type 1 5--reductase. Bioorg Med Chem Lett3:1157-1162 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Synonyms: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 5α-Reductase 1 (5α-R1) | S5A1_HUMAN | S5AR | SR type 1 | SRD5A1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29472.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18405 |
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| Residue: | 259 |
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| Sequence: | MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE
LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA
IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD
TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY
LRKFEEYPKFRKIIIPFLF
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| BDBM50044878 |
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| n/a |
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| Name | BDBM50044878 |
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| Synonyms: | 4,8-Dimethyl-1,4,4a,5,6,10b-hexahydro-2H-benzo[f]quinolin-3-one | CHEMBL134357 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19NO |
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| Mol. Mass. | 229.3175 |
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| SMILES | CN1[C@@H]2CCc3cc(C)ccc3[C@H]2CCC1=O |
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| Structure | 
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