| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Ligand | BDBM50403486 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_66277 |
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| Ki | 258±n/a nM |
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| Citation |  Tatlock, JH; Kalish, VJ; Parge, H; Knighton, DR; Showalter, RE; Lewis, CT; French, J; Villafranca, J High-affinity FKBP-12 ligands derived from (R)-()-carvone. Synthesis and evaluation of FK506 pyranose ring replacements Bioorg Med Chem Lett5:2489-2494 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Synonyms: | 12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B |
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| Type: | Isomerase |
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| Mol. Mass.: | 11953.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62942 |
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| Residue: | 108 |
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| Sequence: | MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW
EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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| BDBM50403486 |
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| n/a |
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| Name | BDBM50403486 |
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| Synonyms: | CHEMBL82427 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H33NO6 |
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| Mol. Mass. | 431.5219 |
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| SMILES | COC[C@@H]1CC[C@@H](C)[C@@](O)(C1)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCc1ccccc1 |
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| Structure | 
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