| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Inosine-5'-monophosphate dehydrogenase 2 |
|---|
| Ligand | BDBM50019476 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_89794 |
|---|
| Ki | 1970±n/a nM |
|---|
| Citation |  Marquez, VE; Tseng, CK; Gebeyehu, G; Cooney, DA; Ahluwalia, GS; Kelley, JA; Dalal, M; Fuller, RW; Wilson, YA; Johns, DG Thiazole-4-carboxamide adenine dinucleotide (TAD). Analogues stable to phosphodiesterase hydrolysis. J Med Chem29:1726-31 (1986) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Inosine-5'-monophosphate dehydrogenase 2 |
|---|
| Name: | Inosine-5'-monophosphate dehydrogenase 2 |
|---|
| Synonyms: | IMDH2_MOUSE | Impdh2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 55818.95 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1297303 |
|---|
| Residue: | 514 |
|---|
| Sequence: | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMT
KREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDA
KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVI
GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
|
|
|
|---|
| BDBM50019476 |
|---|
| n/a |
|---|
| Name | BDBM50019476 |
|---|
| Synonyms: | CHEMBL3144396 | alpha-methylene-Thiazole-4-carboxamide adenine dinucleotide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H27N7O13P2S |
|---|
| Mol. Mass. | 667.48 |
|---|
| SMILES | NC(=O)c1csc(n1)[C@@H]1O[C@H](CCP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
