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Target5-hydroxytryptamine receptor 1D
LigandBDBM50005835
Substrate/Competitorn/a
Meas. Tech.ChEBML_1965
IC50 20±n/a nM
Citation Street, LJBaker, RCastro, JLChambers, MSGuiblin, ARHobbs, SCMatassa, VGReeve, AJBeer, MSMiddlemiss, DN Synthesis and serotonergic activity of 5-(oxadiazolyl)tryptamines: potent agonists for 5-HT1D receptors. J Med Chem36:1529-38 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1D
Name:5-hydroxytryptamine receptor 1D
Synonyms:5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor
Type:PROTEIN
Mol. Mass.:32680.56
Organism:Sus scrofa
Description:ChEMBL_1963
Residue:291
Sequence:
AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAI
TDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIY
STCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSL
HEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVA
SLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
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  Blast E-value cutoff:
BDBM50005835
n/a
NameBDBM50005835
Synonyms:(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide | 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide | 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide | 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide | 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide | CHEMBL128 | SUMATRIPTAN | Sumatran | Sumax
TypeSmall organic molecule
Emp. Form.C14H21N3O2S
Mol. Mass.295.4
SMILESCNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
Structure
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