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TargetSteroid 5-alpha-reductase
LigandBDBM50407307
Substrate/Competitorn/a
Meas. Tech.ChEMBL_204747
Ki 20±n/a nM
Citation Holt DAYamashita DSKonialian-Beck ALLuengo JIAbell ADBergsma DJBrandt MLevy MA Benzophenone- and indolecarboxylic acids: potent type-2 specific inhibitors of human steroid 5 alpha-reductase. J Med Chem 38:13-5 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Steroid 5-alpha-reductase
Name:Steroid 5-alpha-reductase
Synonyms:3-oxo-5-alpha-steroid 4-dehydrogenase 2 | 5 alpha-SR2 | 5α-Reductase 2 (5α-R2) | SR type 2 | Steroid 5-alpha-reductase 2 | Type II 5-alpha reductase
Type:Enzyme
Mol. Mass.:28406.59
Organism:Homo sapiens (Human)
Description:P31213
Residue:254
Sequence:
MQVQCQQSPVLAGSATLVALGALALYVAKPSGYGKHTESLKPAATRLPARAAWFLQELPS
FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVYSLLNRGRPYPAILILRGTAFCT
GNGVLQGYYLIYCAEYPDGWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEISYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
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  Blast E-value cutoff:
BDBM50407307
n/a
NameBDBM50407307
Synonyms:CHEMBL285651
TypeSmall organic molecule
Emp. Form.C20H13NO6
Mol. Mass.363.3203
SMILESOC(=O)c1ccc(cc1)C(=O)c1ccc(Oc2ccc(cc2)[N+]([O-])=O)cc1
Structure
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