| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM81497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2255 (CHEMBL873476) |
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| IC50 | 18620.87±n/a nM |
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| Citation |  Rault, S; Lancelot, JC; Prunier, H; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Guardiola-Lemaitre, B; Hamon, M Novel selective and partial agonists of 5-HT3 receptors. Part 1. Synthesis and biological evaluation of piperazinopyrrolothienopyrazines. J Med Chem39:2068-80 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT2A | 5HT2A_BOVIN | 5HTR2A | HTR2A | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52578.24 |
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| Organism: | BOVINE |
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| Description: | 5-HT2A HTR2A BOVINE::Q75Z89 |
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| Residue: | 470 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV
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| BDBM81497 |
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| n/a |
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| Name | BDBM81497 |
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| Synonyms: | 4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline | CAS_109028-10-6 | CGS 12066B | CHEMBL27403 | NSC_123945 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17F3N4 |
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| Mol. Mass. | 334.3389 |
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| SMILES | CN1CCN(CC1)c1nc2cc(ccc2n2cccc12)C(F)(F)F |
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| Structure | 
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