| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50407789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2254 (CHEMBL617198) |
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| IC50 | 38018.94±n/a nM |
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| Citation |  Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines. J Med Chem40:1808-19 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT2A | 5HT2A_BOVIN | 5HTR2A | HTR2A | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52578.24 |
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| Organism: | BOVINE |
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| Description: | 5-HT2A HTR2A BOVINE::Q75Z89 |
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| Residue: | 470 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV
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| BDBM50407789 |
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| n/a |
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| Name | BDBM50407789 |
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| Synonyms: | CHEMBL52772 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19FN4S |
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| Mol. Mass. | 366.455 |
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| SMILES | Fc1ccc(CN2CCN(CC2)c2nc3sccc3n3cccc23)cc1 |
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| Structure | 
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