| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tubulin alpha-1A chain |
|---|
| Ligand | BDBM50059111 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_212206 (CHEMBL817769) |
|---|
| IC50 | 794.33±n/a nM |
|---|
| Citation |  Zhang, SX; Feng, J; Kuo, SC; Brossi, A; Hamel, E; Tropsha, A; Lee, KH Antitumor agents. 199. Three-dimensional quantitative structure-activity relationship study of the colchicine binding site ligands using comparative molecular field analysis. J Med Chem43:167-76 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tubulin alpha-1A chain |
|---|
| Name: | Tubulin alpha-1A chain |
|---|
| Synonyms: | TBA1A_PIG | TUBA1A | Tubulin | Tubulin alpha chain | Tubulin alpha-1A chain |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 50049.25 |
|---|
| Organism: | Sus scrofa (Pig) |
|---|
| Description: | P02550 |
|---|
| Residue: | 451 |
|---|
| Sequence: | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
|
|
|
|---|
| BDBM50059111 |
|---|
| n/a |
|---|
| Name | BDBM50059111 |
|---|
| Synonyms: | 2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin-4-one | CHEMBL298378 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2O2 |
|---|
| Mol. Mass. | 266.2946 |
|---|
| SMILES | COc1cccc(c1)-c1cc(O)c2cc(C)cnc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
