| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase A1 |
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| Ligand | BDBM50411729 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_465247 (CHEMBL932068) |
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| Ki | 15000±n/a nM |
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| Citation |  Deaton, DN; Gao, EN; Graham, KP; Gross, JW; Miller, AB; Strelow, JM Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett18:732-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase A1 |
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| Name: | Carboxypeptidase A1 |
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| Synonyms: | CBPA1_HUMAN | CPA | CPA1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47132.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1496378 |
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| Residue: | 419 |
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| Sequence: | MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPG
SPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYA
TYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHS
REWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTR
SHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIK
AFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQA
SGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
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| BDBM50411729 |
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| n/a |
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| Name | BDBM50411729 |
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| Synonyms: | CHEMBL269996 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25NO3S |
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| Mol. Mass. | 371.493 |
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| SMILES | CC[C@H](C)[C@H](S)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(O)=O |
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| Structure | 
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