| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50118340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_628657 (CHEMBL1106423) |
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| Ki | 37.15±n/a nM |
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| Citation |  Weber, KC; Salum, LB; Honório, KM; Andricopulo, AD; da Silva, AB Pharmacophore-based 3D QSAR studies on a series of high affinity 5-HT1A receptor ligands. Eur J Med Chem45:1508-14 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50118340 |
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| n/a |
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| Name | BDBM50118340 |
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| Synonyms: | 1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-5-yl)piperazin-1-yl)propan-1-ol | 1-Benzo[b]thiophen-3-yl-3-(4-quinolin-5-yl-piperazin-1-yl)-propan-1-ol | CHEMBL133335 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N3OS |
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| Mol. Mass. | 403.54 |
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| SMILES | OC(CCN1CCN(CC1)c1cccc2ncccc12)c1csc2ccccc12 |
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| Structure | 
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