| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM50417008 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_664775 (CHEMBL1259385) |
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| Ki | 0.446684±n/a nM |
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| Citation |  Vacher, B; Funes, P; Chopin, P; Cussac, D; Heusler, P; Tourette, A; Marien, M Rigid analogues of thea2-adrenergic blocker atipamezole: small changes, big consequences. J Med Chem53:6986-95 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 48979.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08913 |
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| Residue: | 465 |
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| Sequence: | MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM50417008 |
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| n/a |
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| Name | BDBM50417008 |
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| Synonyms: | CHEMBL1255771 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2 |
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| Mol. Mass. | 210.2744 |
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| SMILES | C[C@]12C[C@]1(Cc1ccccc21)c1cnc[nH]1 |r| |
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| Structure | 
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