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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Acetylcholine-binding protein | ||
| Ligand | BDBM50417105 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_665337 (CHEMBL1261014) | ||
| Kd | 24±n/a nM | ||
| Citation |  de Kloe, GE; Retra, K; Geitmann, M; Källblad, P; Nahar, T; van Elk, R; Smit, AB; van Muijlwijk-Koezen, JE; Leurs, R; Irth, H; Danielson, UH; de Esch, IJ Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptora7 ligands. J Med Chem53:7192-201 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Acetylcholine-binding protein | |||
| Name: | Acetylcholine-binding protein | ||
| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP | ||
| Type: | n/a | ||
| Mol. Mass.: | 26055.52 | ||
| Organism: | Lymnaea stagnalis | ||
| Description: | Soluble acetylcholine receptor | ||
| Residue: | 229 | ||
| Sequence: |
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| BDBM50417105 | |||
| n/a | |||
| Name | BDBM50417105 | ||
| Synonyms: | CHEMBL1258240 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H22BrN3O2 | ||
| Mol. Mass. | 416.312 | ||
| SMILES | Brc1ccc(NC(=O)O[C@@H]2C3CCN(CC3)[C@H]2Cc2cccnc2)cc1 |r,wU:9.8,wD:16.18,TLB:17:16:12.11:14.15,THB:8:9:12.11:14.15,(27.75,3.41,;26.42,4.2,;25.08,3.44,;23.76,4.23,;23.78,5.77,;22.46,6.56,;21.11,5.81,;21.09,4.27,;19.79,6.6,;18.44,5.84,;16.97,6.48,;15.62,5.88,;15.35,4.48,;16.71,5.11,;16.46,7.02,;16.9,8.14,;18.25,4.46,;19.01,3.12,;18.23,1.79,;16.69,1.81,;15.91,.49,;16.66,-.85,;18.21,-.86,;18.99,.46,;25.12,6.53,;26.44,5.74,)| | ||
| Structure | 
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