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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H4 receptor | ||
| Ligand | BDBM50419048 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_766544 (CHEMBL1827025) | ||
| Ki | 794.33±n/a nM | ||
| Citation |  Verheij, MH; de Graaf, C; de Kloe, GE; Nijmeijer, S; Vischer, HF; Smits, RA; Zuiderveld, OP; Hulscher, S; Silvestri, L; Thompson, AJ; van Muijlwijk-Koezen, JE; Lummis, SC; Leurs, R; de Esch, IJ Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3A. Bioorg Med Chem Lett21:5460-4 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H4 receptor | |||
| Name: | Histamine H4 receptor | ||
| Synonyms: | AXOR35 | G-protein coupled receptor 105 | GPCR105 | GPRv53 | HH4R | HISTAMINE H4 | HRH4 | HRH4_HUMAN | Histamine H4 receptor | Histamine H4 receptor (H4R) | Histamine receptor (H3 and H4) | Pfi-013 | SP9144 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44517.02 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Binding assays were using CHO cells stably expressing hH4R receptors. | ||
| Residue: | 390 | ||
| Sequence: |
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| BDBM50419048 | |||
| n/a | |||
| Name | BDBM50419048 | ||
| Synonyms: | CHEMBL1824048 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H16ClN3 | ||
| Mol. Mass. | 261.75 | ||
| SMILES | CN1CCC(CC1)=Cc1nc2ccc(Cl)cc2[nH]1 |(32.19,-17.45,;31.42,-18.78,;32.19,-20.12,;31.43,-21.45,;29.89,-21.45,;29.11,-20.13,;29.88,-18.79,;29.13,-22.78,;27.59,-22.79,;26.69,-24.05,;25.22,-23.58,;23.88,-24.36,;22.54,-23.59,;22.55,-22.04,;21.21,-21.27,;23.87,-21.27,;25.21,-22.04,;26.67,-21.55,)| | ||
| Structure | 
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