| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 13 |
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| Ligand | BDBM50420758 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_842608 (CHEMBL2092446) |
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| IC50 | 3±n/a nM |
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| Citation |  Aiguadé, J; Balagué, C; Carranco, I; Caturla, F; Domínguez, M; Eastwood, P; Esteve, C; González, J; Lumeras, W; Orellana, A; Preciado, S; Roca, R; Vidal, L; Vidal, B Novel triazolopyridylbenzamides as potent and selective p38a inhibitors. Bioorg Med Chem Lett22:3431-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 13 |
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| Name: | Mitogen-activated protein kinase 13 |
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| Synonyms: | MAP kinase p38 delta | MAPK13 | MK13_HUMAN | Mitogen-activated protein kinase 13 | Mitogen-activated protein kinase 13 (MAPK13) | Mitogen-activated protein kinase p38 | Mitogen-activated protein kinase p38 delta | PRKM13 | SAPK4 | Stress-activated protein kinase 4 | p38 delta/gamma |
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| Type: | Enzyme |
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| Mol. Mass.: | 42097.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15264 |
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| Residue: | 365 |
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| Sequence: | MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL
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| BDBM50420758 |
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| n/a |
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| Name | BDBM50420758 |
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| Synonyms: | CHEMBL2087503 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21FN4O |
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| Mol. Mass. | 352.4053 |
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| SMILES | CC(C)c1nnc2cc(ccn12)-c1cc(cc(F)c1C)C(=O)NC1CC1 |
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| Structure | 
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