| Reaction Details |
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 | Report a problem with these data |
| Target | Sonic hedgehog protein |
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| Ligand | BDBM50421171 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_839692 (CHEMBL2089519) |
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| EC50 | 500±n/a nM |
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| Citation |  Stappenbeck, F; Xiao, W; Epperson, M; Riley, M; Priest, A; Huang, D; Nguyen, K; Jung, ME; Thies, RS; Farouz, F Novel oxysterols activate the Hedgehog pathway and induce osteogenesis. Bioorg Med Chem Lett22:5893-7 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sonic hedgehog protein |
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| Name: | Sonic hedgehog protein |
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| Synonyms: | Hhg1 | SHH_MOUSE | Shh |
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| Type: | Protein |
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| Mol. Mass.: | 47784.50 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q62226 |
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| Residue: | 437 |
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| Sequence: | MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGAS
GRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPG
VKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKA
HIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLAADDQGRLLYSDFL
TFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAPHNDSGPTPGPSALFASRVRPGQR
VYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAH
RAFAPFRLAHALLAALAPARTDGGGGGSIPAAQSATEARGAEPTAGIHWYSQLLYHIGTW
LLDSETMHPLGMAVKSS
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| BDBM50421171 |
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| n/a |
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| Name | BDBM50421171 |
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| Synonyms: | CHEMBL2086776 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H50O3 |
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| Mol. Mass. | 434.6948 |
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| SMILES | CCCCCCC[C@](C)(O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |r| |
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| Structure | 
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