| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
|---|
| Ligand | BDBM50406762 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1963 |
|---|
| IC50 | 2.0±n/a nM |
|---|
| Citation |  Castro, JL; Matassa, VG; Broughton, HB; Mosley, RT; Street, LJ; Baker, R Synthesis, biological activity and electrostatic properties of 3-[2-(dimethylamino)ethyl]-5-[(3-amino-1,2,4-thiadiazol-5-yl)methyl]-1H-indole, a novel 5-HT1D receptor agonist. Bioorg Med Chem Lett3:993-997 (1993) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1D |
|---|
| Name: | 5-hydroxytryptamine receptor 1D |
|---|
| Synonyms: | 5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 32680.56 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_1963 |
|---|
| Residue: | 291 |
|---|
| Sequence: | AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAI
TDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIY
STCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSL
HEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVA
SLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
|
|
|
|---|
| BDBM50406762 |
|---|
| n/a |
|---|
| Name | BDBM50406762 |
|---|
| Synonyms: | CHEMBL37462 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H19N5S |
|---|
| Mol. Mass. | 301.41 |
|---|
| SMILES | CN(C)CCc1c[nH]c2ccc(Cc3nc(N)ns3)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
