| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
|---|
| Ligand | BDBM50409094 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_123581 (CHEMBL732301) |
|---|
| IC50 | 417±n/a nM |
|---|
| Citation |  Brühlmann, C; Ooms, F; Carrupt, PA; Testa, B; Catto, M; Leonetti, F; Altomare, C; Carotti, A Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase. J Med Chem44:3195-8 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] A |
|---|
| Name: | Amine oxidase [flavin-containing] A |
|---|
| Synonyms: | AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 59515.21 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 526 |
|---|
| Sequence: | MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKL
SSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADR
QAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKD
VPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
|
|
|
|---|
| BDBM50409094 |
|---|
| n/a |
|---|
| Name | BDBM50409094 |
|---|
| Synonyms: | CHEMBL107488 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H16O4 |
|---|
| Mol. Mass. | 296.3172 |
|---|
| SMILES | Cc1c(C)c(=O)oc2cc(OCc3cccc(O)c3)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
