| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50393236 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936102 (CHEMBL2319595) |
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| Temperature | 298.15±n/a K |
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| IC50 | 4060±n/a nM |
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| Comments | extracted |
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| Citation |  Feledziak, M; Michaux, C; Lambert, DM; Marchand-Brynaert, J An unprecedented reversible mode of action ofß-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH). Eur J Med Chem60:101-11 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50393236 |
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| n/a |
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| Name | BDBM50393236 |
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| Synonyms: | CHEMBL2151432 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25NO4 |
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| Mol. Mass. | 343.4168 |
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| SMILES | C[C@@H](OC(=O)CCCc1ccccc1)[C@@H]1CN(C(=O)CCC=C)C1=O |r| |
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| Structure | 
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