| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 3 |
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| Ligand | BDBM50426292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_936438 (CHEMBL2317647) |
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| Ki | 2810±n/a nM |
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| Citation |  Assaf, Z; Larsen, AP; Venskutonyte, R; Han, L; Abrahamsen, B; Nielsen, B; Gajhede, M; Kastrup, JS; Jensen, AA; Pickering, DS; Frydenvang, K; Gefflaut, T; Bunch, L Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. J Med Chem56:1614-28 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, kainate 3 |
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| Name: | Glutamate receptor ionotropic, kainate 3 |
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| Synonyms: | GRIK3_RAT | Glur7 | Glutamate receptor ionotropic kainate 3 | Glutamate receptor ionotropic, kainate | Grik3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 104080.46 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1447329 |
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| Residue: | 919 |
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| Sequence: | MTAPWRRLRSLVWEYWAGFLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAF
RFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNA
VQSICNALEVPHIQLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQSLKWRSATVVYD
DSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQ
ILKQAMAMGMMTEYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNAHVSAIVEKWS
MERLQAAPRAESGLLDGVMMTDAALLYDAVHIVSVCYQRASQMTVNSLQCHRHKPWRFGG
RFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVA
KGRGPNVTDSLTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFS
YEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGV
SILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPG
SEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAF
LTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVK
NNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKIT
IAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAV
GEFIYKLRKTAEREQRSFCSTVADEIRFSLTCQRRLKHKPQPPMMVKTDAVINMHTFNDR
RLPGKDSMSCSTSLAPVFP
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| BDBM50426292 |
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| n/a |
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| Name | BDBM50426292 |
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| Synonyms: | CHEMBL2312402 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N2O6 |
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| Mol. Mass. | 324.3291 |
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| SMILES | N[C@@H](C[C@@H](CCC(=O)NOCc1ccccc1)C(O)=O)C(O)=O |r| |
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| Structure | 
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