| Reaction Details |
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 | Report a problem with these data |
| Target | D-aspartate oxidase |
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| Ligand | BDBM14673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938789 (CHEMBL2327933) |
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| IC50 | 1355000±n/a nM |
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| Citation |  Katane, M; Osaka, N; Matsuda, S; Maeda, K; Kawata, T; Saitoh, Y; Sekine, M; Furuchi, T; Doi, I; Hirono, S; Homma, H Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro. J Med Chem56:1894-907 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-aspartate oxidase |
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| Name: | D-aspartate oxidase |
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| Synonyms: | D-Aspartate Oxidase (DDO) | DASOX | DDO | OXDD_HUMAN |
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| Type: | Oxidoreductase |
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| Mol. Mass.: | 37543.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Recombinant human DDO expressed and purified from sf9 insect cells, was used in enzyme assays. |
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| Residue: | 341 |
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| Sequence: | MDTARIAVVGAGVVGLSTAVCISKLVPRCSVTIISDKFTPDTTSDVAAGMLIPHTYPDTP
IHTQKQWFRETFNHLFAIANSAEAGDAGVHLVSGWQIFQSTPTEEVPFWADVVLGFRKMT
EAELKKFPQYVFGQAFTTLKCECPAYLPWLEKRIKGSGGWTLTRRIEDLWELHPSFDIVV
NCSGLGSRQLAGDSKIFPVRGQVLQVQAPWVEHFIRDGSGLTYIYPGTSHVTLGGTRQKG
DWNLSPDAENSREILSRCCALEPSLHGACNIREKVGLRPYRPGVRLQTELLARDGQRLPV
VHHYGHGSGGISVHWGTALEAARLVSECVHALRTPIPKSNL
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| BDBM14673 |
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| n/a |
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| Name | BDBM14673 |
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| Synonyms: | Fragment 3 | Malonic Acid | propanedioic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C3H4O4 |
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| Mol. Mass. | 104.0615 |
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| SMILES | OC(=O)CC(O)=O |
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| Structure | 
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