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TargetSteroid hormone receptor ERR1
LigandBDBM50427842
Substrate/Competitorn/a
Meas. Tech.ChEMBL_940756 (CHEMBL2330136)
IC50 28±n/a nM
Citation Jiang, XR; Wang, P; Smith, CL; Zhu, BT Synthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity. J Med Chem56:2779-90 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Steroid hormone receptor ERR1
Name:Steroid hormone receptor ERR1
Synonyms:ERR-alpha | ERR1 | ERR1_HUMAN | ESRL1 | ESRRA | Estrogen receptor-like 1 | Estrogen-Related Receptor, alpha | Estrogen-related receptor alpha | NR3B1 | Nuclear receptor subfamily 3 group B member 1 | Steroid hormone receptor ERR1 | Steroid hormone receptor ERR1 alpha | Steroid hormone receptor ERR1/Estrogen-related receptor alpha (ERRa) | von Hippel-Lindau disease tumor suppressor/Steroid hormone receptor ERR1
Type:PROTEIN
Mol. Mass.:45508.08
Organism:Homo sapiens (Human)
Description:ChEMBL_1499891
Residue:423
Sequence:
MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
MMD
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  Blast E-value cutoff:
BDBM50427842
n/a
NameBDBM50427842
Synonyms:CHEMBL2326072
TypeSmall organic molecule
Emp. Form.C34H39NO2
Mol. Mass.493.679
SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCC#Cc1ccc(cc1)-n1cccc1)Cc1cc(O)ccc31 |r|
Structure
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