| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
|---|
| Ligand | BDBM50427838 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_940755 (CHEMBL2330135) |
|---|
| IC50 | 185±n/a nM |
|---|
| Citation |  Jiang, XR; Wang, P; Smith, CL; Zhu, BT Synthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity. J Med Chem56:2779-90 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
|---|
| Name: | Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
|---|
| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | Estrogen-related receptor, beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56220.72 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_940755 |
|---|
| Residue: | 508 |
|---|
| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
TPLNERGRQISPSTRTPGGQGKHLWLTM
|
|
|
|---|
| BDBM50427838 |
|---|
| n/a |
|---|
| Name | BDBM50427838 |
|---|
| Synonyms: | CHEMBL2326076 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C35H42O5 |
|---|
| Mol. Mass. | 542.705 |
|---|
| SMILES | CCOC(=O)CC(=O)c1ccc(cc1)C#CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2CC[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
