| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM50429395 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_948581 (CHEMBL2344671) |
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| EC50 | >10000±n/a nM |
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| Citation |  Pham, TA; Yang, Z; Fang, Y; Luo, J; Lee, J; Park, H Synthesis and biological evaluation of novel 2,4-disubstituted quinazoline analogues as GPR119 agonists. Bioorg Med Chem21:1349-56 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM50429395 |
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| n/a |
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| Name | BDBM50429395 |
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| Synonyms: | CHEMBL2336762 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N4O7S |
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| Mol. Mass. | 572.673 |
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| SMILES | COc1cc2nc(Nc3ccc(cc3)S(C)(=O)=O)nc(OCC3CCN(CC3)C(=O)OC(C)(C)C)c2cc1OC |
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| Structure | 
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