| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
|---|
| Ligand | BDBM50429398 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_948581 (CHEMBL2344671) |
|---|
| EC50 | 1000±n/a nM |
|---|
| Citation |  Pham, TA; Yang, Z; Fang, Y; Luo, J; Lee, J; Park, H Synthesis and biological evaluation of novel 2,4-disubstituted quinazoline analogues as GPR119 agonists. Bioorg Med Chem21:1349-56 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucose-dependent insulinotropic receptor |
|---|
| Name: | Glucose-dependent insulinotropic receptor |
|---|
| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36901.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TDV5 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
|
|
|
|---|
| BDBM50429398 |
|---|
| n/a |
|---|
| Name | BDBM50429398 |
|---|
| Synonyms: | CHEMBL2336759 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H36FN5O6S |
|---|
| Mol. Mass. | 601.689 |
|---|
| SMILES | COc1cc2nc(nc(Nc3ccc(cc3F)S(C)(=O)=O)c2cc1OC)N1CCC2CCC(C1)N2C(=O)OC(C)(C)C |TLB:35:34:33.26.27.28:30.31,6:26:34:30.31| |
|---|
| Structure | 
|
|---|
Search and Browse
