| Reaction Details |
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 | Report a problem with these data |
| Target | Transmembrane protease serine 4 |
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| Ligand | BDBM50430184 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_942945 (CHEMBL2343323) |
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| IC50 | 16000±n/a nM |
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| Citation |  Kang, S; Min, HJ; Kang, MS; Jung, MG; Kim, S Discovery of novel 2-hydroxydiarylamide derivatives as TMPRSS4 inhibitors. Bioorg Med Chem Lett23:1748-51 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transmembrane protease serine 4 |
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| Name: | Transmembrane protease serine 4 |
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| Synonyms: | CAPH2 | Channel-activating protease 2 | MT-SP2 | Membrane-type serine protease 2 | TMPRSS3 | TMPRSS4 | TMPS4_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48237.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_942945 |
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| Residue: | 437 |
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| Sequence: | MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
GPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
KVSAYLNWIYNVWKAEL
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| BDBM50430184 |
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| n/a |
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| Name | BDBM50430184 |
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| Synonyms: | CHEMBL2313095 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11ClF3NO3 |
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| Mol. Mass. | 345.701 |
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| SMILES | COc1cc(NC(=O)c2cc(Cl)ccc2O)cc(c1)C(F)(F)F |
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| Structure | 
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