| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D-amino-acid oxidase |
|---|
| Ligand | BDBM50431070 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_947859 (CHEMBL2343135) |
|---|
| IC50 | 2.2±n/a nM |
|---|
| Citation |  Hondo, T; Warizaya, M; Niimi, T; Namatame, I; Yamaguchi, T; Nakanishi, K; Hamajima, T; Harada, K; Sakashita, H; Matsumoto, Y; Orita, M; Takeuchi, M 4-Hydroxypyridazin-3(2H)-one derivatives as novel D-amino acid oxidase inhibitors. J Med Chem56:3582-92 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D-amino-acid oxidase |
|---|
| Name: | D-amino-acid oxidase |
|---|
| Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
|---|
| Type: | Homodimer |
|---|
| Mol. Mass.: | 39476.06 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14920 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
|
|
|
|---|
| BDBM50431070 |
|---|
| n/a |
|---|
| Name | BDBM50431070 |
|---|
| Synonyms: | CHEMBL2338794 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H10N2O3 |
|---|
| Mol. Mass. | 218.2087 |
|---|
| SMILES | Oc1cc(COc2ccccc2)n[nH]c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
