| Reaction Details |
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 | Report a problem with these data |
| Target | Myc proto-oncogene protein |
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| Ligand | BDBM50431277 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_950755 (CHEMBL2353444) |
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| IC50 | 60000±n/a nM |
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| Citation |  Zaki, MA; Balachandran, P; Khan, S; Wang, M; Mohammed, R; Hetta, MH; Pasco, DS; Muhammad, I Cytotoxicity and modulation of cancer-related signaling by (Z)- and (E)-3,4,3',5'-tetramethoxystilbene isolated from Eugenia rigida. J Nat Prod76:679-84 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Myc proto-oncogene protein |
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| Name: | Myc proto-oncogene protein |
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| Synonyms: | BHLHE39 | Class E basic helix-loop-helix protein 39 | MYC | MYC_HUMAN | Proto-oncogene c-Myc | Transcription factor p64 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48794.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_935266 |
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| Residue: | 439 |
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| Sequence: | MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPP
LSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPD
DETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQD
LSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVL
HEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRC
HVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHN
VLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLL
RKRREQLKHKLEQLRNSCA
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| BDBM50431277 |
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| n/a |
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| Name | BDBM50431277 |
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| Synonyms: | (Z)-3,4,3'',5''-Tetramethoxystilbene | (Z)-3,4,3',5'-TETRAMETHOXYSTILBENE | (Z)-3,5,30,40-Tetramethoxystilbene |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20O4 |
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| Mol. Mass. | 300.349 |
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| SMILES | COc1cc(OC)cc(\C=C/c2ccc(OC)c(OC)c2)c1 |
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| Structure | 
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