| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aminopeptidase N |
|---|
| Ligand | BDBM50353018 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_951229 (CHEMBL2353230) |
|---|
| Ki | 0.350000±n/a nM |
|---|
| Citation |  Schmitt, C; Voegelin, M; Marin, A; Schmitt, M; Schegg, F; Hénon, P; Guenot, D; Tarnus, C Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy. Bioorg Med Chem21:2135-44 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aminopeptidase N |
|---|
| Name: | Aminopeptidase N |
|---|
| Synonyms: | AMPN_HUMAN | ANPEP | APN | Alanyl aminopeptidase | Aminopeptidase | CD13 | CD_antigen=CD13 | Microsomal aminopeptidase | Myeloid plasma membrane glycoprotein CD13 | PEPN | gp150 | hAPN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 109522.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507526 |
|---|
| Residue: | 967 |
|---|
| Sequence: | MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPA
SATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVI
IIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDS
EFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHP
KDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLI
RIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLV
TYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYL
GADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKG
ASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIM
NRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDY
WLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQ
IINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKN
YLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWM
ENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWI
LNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSN
LIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQ
WFTENSK
|
|
|
|---|
| BDBM50353018 |
|---|
| n/a |
|---|
| Name | BDBM50353018 |
|---|
| Synonyms: | CHEMBL1821980 | CHEMBL1852660 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H16BrNO |
|---|
| Mol. Mass. | 330.219 |
|---|
| SMILES | NC1CCc2c(Br)ccc(-c3ccccc3)c2CC1=O |
|---|
| Structure | 
|
|---|
Search and Browse
