Reaction Details | |||
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Target | Cannabinoid receptor 2 | ||
Ligand | BDBM50432194 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_950672 (CHEMBL2352675) | ||
Ki | 588±n/a nM | ||
Citation | Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett23:2019-21 (2013) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Cannabinoid receptor 2 | |||
Name: | Cannabinoid receptor 2 | ||
Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 39690.94 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P34972 | ||
Residue: | 360 | ||
Sequence: |
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BDBM50432194 | |||
n/a | |||
Name | BDBM50432194 | ||
Synonyms: | CHEMBL2346978 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H24N2O3 | ||
Mol. Mass. | 400.4697 | ||
SMILES | COC(=O)c1ccc(Cn2cc(C=C3N4CCC(CC4)C3=O)c3ccccc23)cc1 |w:12.11,(1.09,-40.87,;1.81,-42.23,;3.35,-42.28,;4.08,-43.64,;4.17,-40.97,;3.45,-39.61,;4.26,-38.31,;5.8,-38.36,;6.62,-37.06,;5.9,-35.7,;6.8,-34.45,;5.89,-33.2,;6.37,-31.74,;7.88,-31.42,;8.9,-32.58,;10.4,-32.26,;10.89,-30.8,;9.86,-29.65,;9.81,-30.88,;8.98,-30.94,;8.35,-29.96,;7.32,-28.82,;4.43,-33.68,;3.09,-32.92,;1.76,-33.69,;1.76,-35.23,;3.1,-36,;4.43,-35.22,;6.53,-39.71,;5.72,-41.02,)| | ||
Structure |