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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50432198 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_950673 (CHEMBL2352676) | ||
| Ki | 9.2±n/a nM | ||
| Citation |  Madadi, NR; Penthala, NR; Brents, LK; Ford, BM; Prather, PL; Crooks, PA Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. Bioorg Med Chem Lett23:2019-21 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 52842.52 | ||
| Organism: | Mus musculus (Mouse) | ||
| Description: | P47746 | ||
| Residue: | 473 | ||
| Sequence: |
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| BDBM50432198 | |||
| n/a | |||
| Name | BDBM50432198 | ||
| Synonyms: | CHEMBL240913 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H21FN2O | ||
| Mol. Mass. | 360.424 | ||
| SMILES | Fc1ccc(Cn2cc(C=C3N4CCC(CC4)C3=O)c3ccccc23)cc1 |w:9.8,TLB:9:10:12.13:16.15,THB:18:17:12.13:16.15,(2.73,-28.57,;1.19,-28.57,;.42,-29.91,;-1.12,-29.91,;-1.88,-28.57,;-3.42,-28.57,;-4.19,-27.24,;-3.28,-25.98,;-4.19,-24.73,;-3.43,-23.39,;-1.89,-23.38,;-.56,-24.38,;-.42,-25.88,;.65,-24.95,;.5,-23.47,;1.96,-22.72,;1.22,-23.66,;-.79,-22.52,;-.81,-20.98,;-5.67,-25.21,;-7,-24.44,;-8.33,-25.22,;-8.33,-26.76,;-7,-27.53,;-5.67,-26.76,;-1.12,-27.24,;.41,-27.23,)| | ||
| Structure | 
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