| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene C4 synthase |
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| Ligand | BDBM50434668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_961179 (CHEMBL2389915) |
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| IC50 | >3000±n/a nM |
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| Citation |  Shiro, T; Kakiguchi, K; Takahashi, H; Nagata, H; Tobe, M 7-Phenyl-imidazoquinolin-4(5H)-one derivatives as selective and orally available mPGES-1 inhibitors. Bioorg Med Chem21:2868-78 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene C4 synthase |
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| Name: | Leukotriene C4 synthase |
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| Synonyms: | LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 16575.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_961179 |
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| Residue: | 150 |
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| Sequence: | MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
LAALGLLAHFLPAALRAALLGRLRTLLPWA
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| BDBM50434668 |
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| n/a |
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| Name | BDBM50434668 |
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| Synonyms: | CHEMBL2387503 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H13ClFN3O |
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| Mol. Mass. | 389.81 |
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| SMILES | Fc1cccc(Cl)c1-c1nc2c([nH]1)c(=O)[nH]c1cc(ccc21)-c1ccccc1 |
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| Structure | 
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