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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transient receptor potential cation channel subfamily V member 1 | ||
| Ligand | BDBM50434908 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_960514 (CHEMBL2389489) | ||
| Ki | 1.000000±n/a nM | ||
| Citation |  Thorat, SA; Kang, DW; Ryu, H; Kim, MS; Kim, HS; Ann, J; Ha, T; Kim, SE; Son, K; Choi, S; Blumberg, PM; Frank, R; Bahrenberg, G; Schiene, K; Christoph, T; Lee, J 2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: structure activity relationships of the 2-oxy pyridine C-region. Eur J Med Chem64:589-602 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transient receptor potential cation channel subfamily V member 1 | |||
| Name: | Transient receptor potential cation channel subfamily V member 1 | ||
| Synonyms: | Capsaicin receptor | OTRPC1 | Osm-9-like TRP channel 1 | TRPV1 | TRPV1_HUMAN | Transient receptor potential cation channel subfamily V member 1 | Transient receptor potential cation channel subfamily V member 1 (TRPV1) | Transient receptor potential cation channel subfamily V member 1 (VR1/TRPV1) | Transient receptor potential cation channel subfamily V member 1(TRPV1) | VR1 | Vanilloid VR1 | Vanilloid receptor | Vanilloid receptor 1 | Vanilloid receptor 1 (TrpV1/Vr1) | Vanilloid receptor 1 (VRI/TRPV1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 94960.75 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q8NER1 | ||
| Residue: | 839 | ||
| Sequence: |
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| BDBM50434908 | |||
| n/a | |||
| Name | BDBM50434908 | ||
| Synonyms: | CHEMBL2385251 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H31F4N3O4S | ||
| Mol. Mass. | 545.59 | ||
| SMILES | CC(C(=O)NCc1ccc(nc1OCC1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(52.24,-26.93,;52.24,-28.47,;50.91,-29.24,;50.91,-30.78,;49.57,-28.47,;48.24,-29.25,;46.91,-28.48,;46.9,-26.93,;45.57,-26.16,;44.24,-26.93,;44.23,-28.48,;45.57,-29.25,;45.57,-30.79,;46.91,-31.55,;46.91,-33.09,;45.58,-33.85,;45.58,-35.39,;46.92,-36.16,;46.92,-37.7,;48.25,-35.39,;48.25,-33.84,;42.9,-26.16,;42.9,-24.62,;41.57,-26.93,;41.56,-25.39,;53.58,-29.24,;53.57,-30.78,;54.9,-31.55,;56.24,-30.77,;57.57,-31.54,;58.9,-30.77,;60.24,-31.53,;58.12,-29.42,;59.66,-29.42,;56.23,-29.23,;57.56,-28.45,;54.9,-28.46,)| | ||
| Structure | 
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