| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM85035 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_965439 (CHEMBL2395085) |
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| Ki | 0.150000±n/a nM |
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| Citation |  Germain, AR; Carmody, LC; Nag, PP; Morgan, B; Verplank, L; Fernandez, C; Donckele, E; Feng, Y; Perez, JR; Dandapani, S; Palmer, M; Lander, ES; Gupta, PB; Schreiber, SL; Munoz, B Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells. Bioorg Med Chem Lett23:1834-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM85035 |
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| n/a |
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| Name | BDBM85035 |
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| Synonyms: | CAS_65154-06-5 | PAF | bloodplatelet-activatingfactor |
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| Type | Small organic molecule |
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| Emp. Form. | C26H54NO7P |
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| Mol. Mass. | 523.6832 |
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| SMILES | CCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(C)=O |r| |
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| Structure | 
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