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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Phosphatidylinositol 4-kinase beta | ||
| Ligand | BDBM50005004 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_966466 | ||
| IC50 | 22±n/a nM | ||
| Citation |  Décor A; Grand-Maître C; Hucke O; O'Meara J; Kuhn C; Constantineau-Forget L; Brochu C; Malenfant E; Bertrand-Laperle M; Bordeleau J; Ghiro E; Pesant M; Fazal G; Gorys V; Little M; Boucher C; Bordeleau S; Turcotte P; Guo T; Garneau M; Spickler C; Gauthier A Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus. Bioorg Med Chem Lett 23:3841-7 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Phosphatidylinositol 4-kinase beta | |||
| Name: | Phosphatidylinositol 4-kinase beta | ||
| Synonyms: | NPIK | PI4-kinase beta subunit | PI4K-beta | PI4K92 | PI4Kbeta | PIK4B | PIK4CB | Phosphatidylinositol 4-kinase, PI4K | PtdIns 4-kinase beta | ||
| Type: | Protein | ||
| Mol. Mass.: | 91373.30 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 816 | ||
| Sequence: |
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| BDBM50005004 | |||
| n/a | |||
| Name | BDBM50005004 | ||
| Synonyms: | CHEMBL2397309 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H22N4O2S | ||
| Mol. Mass. | 346.447 | ||
| SMILES | CO[C@H]1CC[C@H](CC1)C(=O)Nc1nc(C)c(s1)-c1ccc(N)nc1 |r,wU:5.8,2.1,(18.48,-29.12,;17.85,-27.71,;16.32,-27.55,;15.42,-28.8,;13.89,-28.64,;13.26,-27.23,;14.16,-25.98,;15.69,-26.14,;11.73,-27.08,;10.83,-28.32,;11.1,-25.67,;9.57,-25.52,;8.79,-24.19,;7.29,-24.51,;6.14,-23.48,;7.13,-26.04,;8.54,-26.66,;5.8,-26.81,;4.46,-26.05,;3.13,-26.82,;3.13,-28.36,;1.8,-29.13,;4.46,-29.13,;5.8,-28.36,)| | ||
| Structure | 
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