| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17A |
|---|
| Ligand | BDBM50436478 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_966451 (CHEMBL2399039) |
|---|
| IC50 | 2900±n/a nM |
|---|
| Citation |  Décor, A; Grand-Maître, C; Hucke, O; O'Meara, J; Kuhn, C; Constantineau-Forget, L; Brochu, C; Malenfant, E; Bertrand-Laperle, M; Bordeleau, J; Ghiro, E; Pesant, M; Fazal, G; Gorys, V; Little, M; Boucher, C; Bordeleau, S; Turcotte, P; Guo, T; Garneau, M; Spickler, C; Gauthier, A Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus. Bioorg Med Chem Lett23:3841-7 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase 17A |
|---|
| Name: | Serine/threonine-protein kinase 17A |
|---|
| Synonyms: | DRAK1 | ST17A_HUMAN | STK17A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46544.04 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_109255245 |
|---|
| Residue: | 414 |
|---|
| Sequence: | MIPLEKPGSGGSSPGATSGSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYS
LCPGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPW
VINLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTR
DVVHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPI
SMATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRT
LLVKKPEDRATAEECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSE
TKESIVTEELIVVTSYTLGQCRQSEKEKMEQKAISKRFKFEEPLLQEIPGEFIY
|
|
|
|---|
| BDBM50436478 |
|---|
| n/a |
|---|
| Name | BDBM50436478 |
|---|
| Synonyms: | CHEMBL2397314 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H15F3N4OS |
|---|
| Mol. Mass. | 344.355 |
|---|
| SMILES | C[C@H](CC(F)(F)F)C(=O)Nc1nc(C)c(s1)-c1ccc(N)nc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
