| Reaction Details |
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 | Report a problem with these data |
| Target | Acrosin |
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| Ligand | BDBM50436597 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_967179 (CHEMBL2399923) |
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| IC50 | 330000±n/a nM |
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| Citation |  Tian, W; Han, G; Zhu, J; Qi, J; Chen, Q; Zhao, J; Zheng, C; Zhang, L; Zhou, Y; Lv, J Synthesis and acrosin inhibitory activities of 5-phenyl-1H-pyrazole-3-carboxylic acid amide derivatives. Bioorg Med Chem Lett23:4177-84 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acrosin |
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| Name: | Acrosin |
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| Synonyms: | ACR | ACRO_HUMAN | ACRS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45865.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1365286 |
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| Residue: | 421 |
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| Sequence: | MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSA
TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
S
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| BDBM50436597 |
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| n/a |
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| Name | BDBM50436597 |
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| Synonyms: | CHEMBL2397948 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14BrN3O2 |
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| Mol. Mass. | 324.173 |
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| SMILES | CC(O)CNC(=O)c1cc(n[nH]1)-c1ccc(Br)cc1 |
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| Structure | 
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