| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50292604 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_969180 (CHEMBL2404437) |
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| Ki | 1400±n/a nM |
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| Citation |  Darvesh, S; Macdonald, IR; Martin, E Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems. Bioorg Med Chem Lett23:3822-5 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50292604 |
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| n/a |
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| Name | BDBM50292604 |
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| Synonyms: | 3-(diethylamino)propyl 10H-phenothiazine-10-carboxylate | CHEMBL519609 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O2S |
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| Mol. Mass. | 356.482 |
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| SMILES | CCN(CC)CCCOC(=O)N1c2ccccc2Sc2ccccc12 |
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| Structure | 
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