| Reaction Details |
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 | Report a problem with these data |
| Target | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Ligand | BDBM50438422 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_975738 (CHEMBL2415236) |
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| IC50 | 2738±n/a nM |
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| Citation |  Choi, D; Piao, YL; Wu, Y; Cho, H Control of the intracellular levels of prostaglandin E2 through inhibition of the 15-hydroxyprostaglandin dehydrogenase for wound healing. Bioorg Med Chem21:4477-84 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Name: | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
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| Synonyms: | 15-PGDH | 15-hydroxyprostaglandin dehydrogenase [NAD+] | HPGD | PGDH1 | PGDH_HUMAN | Prostaglandin dehydrogenase 1 (15-PGDH) | SDR36C1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 28974.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15428 |
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| Residue: | 266 |
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| Sequence: | MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF
IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD
YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA
ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG
AIMKITTSKGIHFQDYDTTPFQAKTQ
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| BDBM50438422 |
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| n/a |
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| Name | BDBM50438422 |
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| Synonyms: | CHEMBL2414141 | US8637558, 94 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16ClNO4S |
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| Mol. Mass. | 341.81 |
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| SMILES | CC(C)OCCOc1ccc(C=C2SC(O)=NC2=O)cc1Cl |w:11.10,c:15| |
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| Structure | 
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