| Reaction Details |
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 | Report a problem with these data |
| Target | Aminopeptidase N |
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| Ligand | BDBM50438623 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_976041 (CHEMBL2415690) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Ma, C; Li, X; Liang, X; Jin, K; Cao, J; Xu, W Novelß-dicarbonyl derivatives as inhibitors of aminopeptidase N (APN). Bioorg Med Chem Lett23:4948-52 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminopeptidase N |
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| Name: | Aminopeptidase N |
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| Synonyms: | AMPN_PIG | ANPEP | AP-M | AP-N | Alanyl aminopeptidase | Aminopeptidase M | Aminopeptidase N (APN) | CD_antigen=CD13 | Microsomal aminopeptidase | gp130 | pAPN |
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| Type: | Protein |
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| Mol. Mass.: | 108810.25 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P15145 |
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| Residue: | 963 |
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| Sequence: | MAKGFYISKALGILGILLGVAAVATIIALSVVYAQEKNKNAEHVPQAPTSPTITTTAAIT
LDQSKPWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRLLCQEPTDVIIIHS
KKLNYTTQGHMVVLRGVGDSQVPEIDRTELVELTEYLVVHLKGSLQPGHMYEMESEFQGE
LADDLAGFYRSEYMEGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTA
LSNMPPKGSSTPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIWAR
PNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYREN
ALLFDPQSSSISNKERVVTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYVEYLGADHA
EPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKGASVIR
MLSNFLTEDLFKEGLASYLHAFAYQNTTYLDLWEHLQKAVDAQTSIRLPDTVRAIMDRWT
LQMGFPVITVDTKTGNISQKHFLLDSESNVTRSSAFDYLWIVPISSIKNGVMQDHYWLRD
VSQAQNDLFKTASDDWVLLNVNVTGYFQVNYDEDNWRMIQHQLQTNLSVIPVINRAQVIY
DSFNLATAHMVPVTLALDNTLFLNGEKEYMPWQAALSSLSYFSLMFDRSEVYGPMKKYLR
KQVEPLFQHFETLTKNWTERPENLMDQYSEINAISTACSNGLPQCENLAKTLFDQWMSDP
ENNPIHPNLRSTIYCNAIAQGGQDQWDFAWGQLQQAQLVNEADKLRSALACSNEVWLLNR
YLGYTLNPDLIRKQDATSTINSIASNVIGQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQ
GVTRRFSSEFELQQLEQFKKNNMDVGFGSGTRALEQALEKTKANIKWVKENKEVVLNWFI
EHS
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| BDBM50438623 |
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| n/a |
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| Name | BDBM50438623 |
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| Synonyms: | CHEMBL2414229 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H34N2O6 |
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| Mol. Mass. | 434.5259 |
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| SMILES | COC(=O)[C@H](CC(C)C)NC(=O)CC(=O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C |r| |
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| Structure | 
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