| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50441676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_988143 (CHEMBL2439234) |
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| IC50 | >10000±n/a nM |
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| Citation |  Ribeiro, CJ; Kumar, SP; Gut, J; Gonçalves, LM; Rosenthal, PJ; Moreira, R; Santos, MM Squaric acid/4-aminoquinoline conjugates: novel potent antiplasmodial agents. Eur J Med Chem69:365-72 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50441676 |
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| n/a |
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| Name | BDBM50441676 |
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| Synonyms: | CHEMBL2435704 |
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| Type | Small organic molecule |
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| Emp. Form. | C44H40Cl2N8O4 |
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| Mol. Mass. | 815.746 |
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| SMILES | Clc1ccc2c(NCCNC(=O)[C@H](Cc3ccccc3)Nc3c(N[C@@H](Cc4ccccc4)C(=O)NCCNc4ccnc5cc(Cl)ccc45)c(=O)c3=O)ccnc2c1 |r| |
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| Structure | 
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