| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50441933 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_987953 (CHEMBL2438376) |
|---|
| Ki | 311±n/a nM |
|---|
| Citation |  Abate, C; Selivanova, SV; Müller, A; Krämer, SD; Schibli, R; Marottoli, R; Perrone, R; Berardi, F; Niso, M; Ametamey, SM Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging ofs2 receptors. Eur J Med Chem69:920-30 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 25307.17 |
|---|
| Organism: | Cavia porcellus (Guinea pig) |
|---|
| Description: | Q60492 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
|
|
|
|---|
| BDBM50441933 |
|---|
| n/a |
|---|
| Name | BDBM50441933 |
|---|
| Synonyms: | CHEMBL2437383 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H27FN2O3 |
|---|
| Mol. Mass. | 398.4705 |
|---|
| SMILES | COc1cc2CCN(CCCN3CCc4cc(F)ccc4C3=O)Cc2cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
