Found 187 hits with Last Name = 'schibli' and Initial = 'r' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072352
(CHEMBL3409318)Show SMILES CCOCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(OC)c12 |TLB:18:13:20:17.19.16,18:17:20:12.13.14,THB:16:15:12:18.17.19,16:17:12:20.14.15| Show InChI InChI=1S/C25H32N2O4/c1-3-31-8-7-27-15-20(23(28)19-5-4-6-21(30-2)22(19)27)24(29)26-25-12-16-9-17(13-25)11-18(10-16)14-25/h4-6,15-18H,3,7-14H2,1-2H3,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072350
(CHEMBL3409320)Show SMILES CCOCCn1cc(C(=O)NC23CC4CC(CC(O)(C4)C2)C3)c(=O)c2cccc(OC)c12 |TLB:14:15:12.13.19:20,19:13:21:17.20.16,19:17:21:12.13.14| Show InChI InChI=1S/C25H32N2O5/c1-3-32-8-7-27-14-19(22(28)18-5-4-6-20(31-2)21(18)27)23(29)26-24-10-16-9-17(11-24)13-25(30,12-16)15-24/h4-6,14,16-17,30H,3,7-13,15H2,1-2H3,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50350151
(CHEMBL1814458)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(OC)c12 |TLB:10:11:14.13.18:16,THB:12:13:16:20.11.19,12:11:14.13.18:16,19:11:14:18.17.16,19:17:14:20.12.11| Show InChI InChI=1S/C26H34N2O3/c1-3-4-5-9-28-16-21(24(29)20-7-6-8-22(31-2)23(20)28)25(30)27-26-13-17-10-18(14-26)12-19(11-17)15-26/h6-8,16-19H,3-5,9-15H2,1-2H3,(H,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090950
(CHEMBL3582008)Show SMILES CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1 Show InChI InChI=1S/C22H33N3O5/c1-5-22(6-2,21(27)29-7-3)24-19(26)17-10-11-18(25-12-16(13-25)28-4)20(23-17)30-14-15-8-9-15/h10-11,15-16H,5-9,12-14H2,1-4H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090950
(CHEMBL3582008)Show SMILES CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1 Show InChI InChI=1S/C22H33N3O5/c1-5-22(6-2,21(27)29-7-3)24-19(26)17-10-11-18(25-12-16(13-25)28-4)20(23-17)30-14-15-8-9-15/h10-11,15-16H,5-9,12-14H2,1-4H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090950
(CHEMBL3582008)Show SMILES CCOC(=O)C(CC)(CC)NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1 Show InChI InChI=1S/C22H33N3O5/c1-5-22(6-2,21(27)29-7-3)24-19(26)17-10-11-18(25-12-16(13-25)28-4)20(23-17)30-14-15-8-9-15/h10-11,15-16H,5-9,12-14H2,1-4H3,(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50035131
((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)Show SMILES [#6]-[#6@@H]1-[#6@@H]-2-[#6]-c3ccc(-[#8])cc3[C@@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |r,TLB:16:15:10.4.3:1| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari ALDO MORO
Curated by ChEMBL
| Assay Description
Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in Dunkin guinea pig brain membranes without cerebellum |
Eur J Med Chem 69: 920-30 (2013)
Article DOI: 10.1016/j.ejmech.2013.09.018
BindingDB Entry DOI: 10.7270/Q2K64KH7 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072357
(CHEMBL3409149)Show SMILES CCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(OC)c12 |TLB:17:12:19:16.18.15,17:16:19:11.12.13,THB:15:14:11:17.16.18,15:16:11:19.13.14| Show InChI InChI=1S/C25H32N2O3/c1-3-4-8-27-15-20(23(28)19-6-5-7-21(30-2)22(19)27)24(29)26-25-12-16-9-17(13-25)11-18(10-16)14-25/h5-7,15-18H,3-4,8-14H2,1-2H3,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50395548
(CHEMBL2164783)Show InChI InChI=1S/C14H13FN2O/c1-18-17-14-10-11(6-8-13(14)15)5-7-12-4-2-3-9-16-12/h2-4,9-10,13H,6,8H2,1H3/b17-14- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich
Curated by ChEMBL
| Assay Description
Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting |
J Med Chem 55: 7154-62 (2012)
Article DOI: 10.1021/jm300648b
BindingDB Entry DOI: 10.7270/Q2ST7QZX |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072349
(CHEMBL3409322)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3Cl)c(C)c(CCN3CCOCC3)c2c1 Show InChI InChI=1S/C23H24Cl2N2O3/c1-15-18(7-8-26-9-11-30-12-10-26)20-14-17(29-2)4-6-22(20)27(15)23(28)19-5-3-16(24)13-21(19)25/h3-6,13-14H,7-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to human CB2 receptor |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50234418
((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)Show SMILES COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1 Show InChI InChI=1S/C23H24Cl2N2O3/c1-15-17(8-9-26-10-12-30-13-11-26)19-14-16(29-2)6-7-21(19)27(15)23(28)18-4-3-5-20(24)22(18)25/h3-7,14H,8-13H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Binding affinity to human CB2 receptor |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50395546
(CHEMBL2164785)Show InChI InChI=1S/C15H15FN2O/c1-2-19-18-15-11-12(7-9-14(15)16)6-8-13-5-3-4-10-17-13/h3-5,10-11,14H,2,7,9H2,1H3/b18-15- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich
Curated by ChEMBL
| Assay Description
Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting |
J Med Chem 55: 7154-62 (2012)
Article DOI: 10.1021/jm300648b
BindingDB Entry DOI: 10.7270/Q2ST7QZX |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090922
(CHEMBL3582012)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)N1CC(F)C1 Show InChI InChI=1S/C23H33FN4O4/c1-4-23(5-2,22(30)28-10-16(24)11-28)26-20(29)18-8-9-19(27-12-17(13-27)31-3)21(25-18)32-14-15-6-7-15/h8-9,15-17H,4-7,10-14H2,1-3H3,(H,26,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072356
(CHEMBL3409150)Show InChI InChI=1S/C19H26N2O3/c1-6-7-11-21-12-14(18(23)20-19(2,3)4)17(22)13-9-8-10-15(24-5)16(13)21/h8-10,12H,6-7,11H2,1-5H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50395547
(CHEMBL2164784)Show InChI InChI=1S/C15H15FN2O/c1-11-4-3-5-13(17-11)8-6-12-7-9-14(16)15(10-12)18-19-2/h3-5,10,14H,7,9H2,1-2H3/b18-15- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich
Curated by ChEMBL
| Assay Description
Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting |
J Med Chem 55: 7154-62 (2012)
Article DOI: 10.1021/jm300648b
BindingDB Entry DOI: 10.7270/Q2ST7QZX |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090956
(CHEMBL3582027)Show SMILES CCOCCOCC(C)(C)c1cc(NC(=O)c2ccc(C3CCCC3)c(OCC3CC3)n2)on1 Show InChI InChI=1S/C26H37N3O5/c1-4-31-13-14-32-17-26(2,3)22-15-23(34-29-22)28-24(30)21-12-11-20(19-7-5-6-8-19)25(27-21)33-16-18-9-10-18/h11-12,15,18-19H,4-10,13-14,16-17H2,1-3H3,(H,28,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090955
(CHEMBL3582026)Show SMILES COCCOCC(C)(C)c1cc(NC(=O)c2ccc(C3CCCC3)c(OCC3CC3)n2)on1 Show InChI InChI=1S/C25H35N3O5/c1-25(2,16-31-13-12-30-3)21-14-22(33-28-21)27-23(29)20-11-10-19(18-6-4-5-7-18)24(26-20)32-15-17-8-9-17/h10-11,14,17-18H,4-9,12-13,15-16H2,1-3H3,(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50395545
(CHEMBL2164787)Show InChI InChI=1S/C16H17FN2O/c1-3-20-19-16-11-13(8-10-15(16)17)7-9-14-6-4-5-12(2)18-14/h4-6,11,15H,3,8,10H2,1-2H3/b19-16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich
Curated by ChEMBL
| Assay Description
Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting |
J Med Chem 55: 7154-62 (2012)
Article DOI: 10.1021/jm300648b
BindingDB Entry DOI: 10.7270/Q2ST7QZX |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090953
(CHEMBL3582024)Show SMILES CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1 Show InChI InChI=1S/C23H34N2O4/c1-4-23(5-2,22(27)28-6-3)25-20(26)19-14-13-18(17-9-7-8-10-17)21(24-19)29-15-16-11-12-16/h13-14,16-17H,4-12,15H2,1-3H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090922
(CHEMBL3582012)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)N1CC(F)C1 Show InChI InChI=1S/C23H33FN4O4/c1-4-23(5-2,22(30)28-10-16(24)11-28)26-20(29)18-8-9-19(27-12-17(13-27)31-3)21(25-18)32-14-15-6-7-15/h8-9,15-17H,4-7,10-14H2,1-3H3,(H,26,29) | PDB
Reactome pathway
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PC sid
UniChem
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PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072355
(CHEMBL3409151)Show InChI InChI=1S/C20H26N2O3/c1-3-4-12-22-13-16(20(24)21-14-8-5-6-9-14)19(23)15-10-7-11-17(25-2)18(15)22/h7,10-11,13-14H,3-6,8-9,12H2,1-2H3,(H,21,24) | PDB
Reactome pathway
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UniChem
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| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat)) | BDBM50395544
(CHEMBL2164788)Show InChI InChI=1S/C15H15FN2O/c1-2-19-18-15-11-12(7-9-14(15)16)6-8-13-5-3-4-10-17-13/h3-5,10-11,14H,2,7,9H2,1H3/b18-15+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 31.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology (ETH) Zurich
Curated by ChEMBL
| Assay Description
Displacement of [3H]-ABP688 from mGluR5 receptor in Sprague-Dawley rat brain after 45 mins by beta counting |
J Med Chem 55: 7154-62 (2012)
Article DOI: 10.1021/jm300648b
BindingDB Entry DOI: 10.7270/Q2ST7QZX |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090953
(CHEMBL3582024)Show SMILES CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1 Show InChI InChI=1S/C23H34N2O4/c1-4-23(5-2,22(27)28-6-3)25-20(26)19-14-13-18(17-9-7-8-10-17)21(24-19)29-15-16-11-12-16/h13-14,16-17H,4-12,15H2,1-3H3,(H,25,26) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090949
(CHEMBL3582009)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)NC Show InChI InChI=1S/C21H32N4O4/c1-5-21(6-2,20(27)22-3)24-18(26)16-9-10-17(25-11-15(12-25)28-4)19(23-16)29-13-14-7-8-14/h9-10,14-15H,5-8,11-13H2,1-4H3,(H,22,27)(H,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090954
(CHEMBL3582025)Show SMILES CC(C)(OC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1)c1cc(N)on1 Show InChI InChI=1S/C21H27N3O4/c1-21(2,17-11-18(22)28-24-17)27-20(25)16-10-9-15(14-5-3-4-6-14)19(23-16)26-12-13-7-8-13/h9-11,13-14H,3-8,12,22H2,1-2H3 | PDB
Reactome pathway
KEGG
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UniChem
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| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072354
(CHEMBL3409152)Show InChI InChI=1S/C19H24N2O3/c1-3-4-10-21-12-15(19(23)20-11-13-8-9-13)18(22)14-6-5-7-16(24-2)17(14)21/h5-7,12-13H,3-4,8-11H2,1-2H3,(H,20,23) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090949
(CHEMBL3582009)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)NC Show InChI InChI=1S/C21H32N4O4/c1-5-21(6-2,20(27)22-3)24-18(26)16-9-10-17(25-11-15(12-25)28-4)19(23-16)29-13-14-7-8-14/h9-10,14-15H,5-8,11-13H2,1-4H3,(H,22,27)(H,24,26) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090963
(CHEMBL3582018 | US9290451, 86)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC Show InChI InChI=1S/C20H28F2N4O3/c1-4-19(5-2,18(28)23-3)25-16(27)14-8-9-15(26-11-20(21,22)12-26)17(24-14)29-10-13-6-7-13/h8-9,13H,4-7,10-12H2,1-3H3,(H,23,28)(H,25,27) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 179 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090963
(CHEMBL3582018 | US9290451, 86)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC Show InChI InChI=1S/C20H28F2N4O3/c1-4-19(5-2,18(28)23-3)25-16(27)14-8-9-15(26-11-20(21,22)12-26)17(24-14)29-10-13-6-7-13/h8-9,13H,4-7,10-12H2,1-3H3,(H,23,28)(H,25,27) | PDB
Reactome pathway
KEGG
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| CHEMBL
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UniChem
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| Article
PubMed
| 245 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090956
(CHEMBL3582027)Show SMILES CCOCCOCC(C)(C)c1cc(NC(=O)c2ccc(C3CCCC3)c(OCC3CC3)n2)on1 Show InChI InChI=1S/C26H37N3O5/c1-4-31-13-14-32-17-26(2,3)22-15-23(34-29-22)28-24(30)21-12-11-20(19-7-5-6-8-19)25(27-21)33-16-18-9-10-18/h11-12,15,18-19H,4-10,13-14,16-17H2,1-3H3,(H,28,30) | PDB
Reactome pathway
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UniChem
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| 264 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090955
(CHEMBL3582026)Show SMILES COCCOCC(C)(C)c1cc(NC(=O)c2ccc(C3CCCC3)c(OCC3CC3)n2)on1 Show InChI InChI=1S/C25H35N3O5/c1-25(2,16-31-13-12-30-3)21-14-22(33-28-21)27-23(29)20-11-10-19(18-6-4-5-7-18)24(26-20)32-15-17-8-9-17/h10-11,14,17-18H,4-9,12-13,15-16H2,1-3H3,(H,27,29) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 294 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50441933
(CHEMBL2437383)Show InChI InChI=1S/C23H27FN2O3/c1-28-21-13-16-6-10-25(15-18(16)14-22(21)29-2)8-3-9-26-11-7-17-12-19(24)4-5-20(17)23(26)27/h4-5,12-14H,3,6-11,15H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 311 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari ALDO MORO
Curated by ChEMBL
| Assay Description
Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in Dunkin guinea pig brain membranes without cerebellum |
Eur J Med Chem 69: 920-30 (2013)
Article DOI: 10.1016/j.ejmech.2013.09.018
BindingDB Entry DOI: 10.7270/Q2K64KH7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090954
(CHEMBL3582025)Show SMILES CC(C)(OC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1)c1cc(N)on1 Show InChI InChI=1S/C21H27N3O4/c1-21(2,17-11-18(22)28-24-17)27-20(25)16-10-9-15(14-5-3-4-6-14)19(23-16)26-12-13-7-8-13/h9-11,13-14H,3-8,12,22H2,1-2H3 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Patents
| Article
PubMed
| 352 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072351
(CHEMBL3409319)Show SMILES CCOCCn1cc(C(=O)NCCc2ccccc2)c(=O)c2cccc(OC)c12 Show InChI InChI=1S/C23H26N2O4/c1-3-29-15-14-25-16-19(22(26)18-10-7-11-20(28-2)21(18)25)23(27)24-13-12-17-8-5-4-6-9-17/h4-11,16H,3,12-15H2,1-2H3,(H,24,27) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Patents
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| Article
PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50441936
(CHEMBL2437384)Show SMILES COc1ccc2C(=O)N(CCCN3CCc4cc(OC)c(OC)cc4C3)CCc2c1 Show InChI InChI=1S/C24H30N2O4/c1-28-20-5-6-21-18(13-20)8-12-26(24(21)27)10-4-9-25-11-7-17-14-22(29-2)23(30-3)15-19(17)16-25/h5-6,13-15H,4,7-12,16H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 402 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari ALDO MORO
Curated by ChEMBL
| Assay Description
Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in Dunkin guinea pig brain membranes without cerebellum |
Eur J Med Chem 69: 920-30 (2013)
Article DOI: 10.1016/j.ejmech.2013.09.018
BindingDB Entry DOI: 10.7270/Q2K64KH7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090964
(CHEMBL3582019)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NCCF Show InChI InChI=1S/C21H29F3N4O3/c1-3-20(4-2,19(30)25-10-9-22)27-17(29)15-7-8-16(28-12-21(23,24)13-28)18(26-15)31-11-14-5-6-14/h7-8,14H,3-6,9-13H2,1-2H3,(H,25,30)(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 403 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090957
(CHEMBL3582028)Show SMILES CC(C)(Cc1nnc(o1)-c1ccc(F)cc1)NC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1 Show InChI InChI=1S/C27H31FN4O3/c1-27(2,15-23-31-32-25(35-23)19-9-11-20(28)12-10-19)30-24(33)22-14-13-21(18-5-3-4-6-18)26(29-22)34-16-17-7-8-17/h9-14,17-18H,3-8,15-16H2,1-2H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 403 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090957
(CHEMBL3582028)Show SMILES CC(C)(Cc1nnc(o1)-c1ccc(F)cc1)NC(=O)c1ccc(C2CCCC2)c(OCC2CC2)n1 Show InChI InChI=1S/C27H31FN4O3/c1-27(2,15-23-31-32-25(35-23)19-9-11-20(28)12-10-19)30-24(33)22-14-13-21(18-5-3-4-6-18)26(29-22)34-16-17-7-8-17/h9-14,17-18H,3-8,15-16H2,1-2H3,(H,30,33) | PDB
Reactome pathway
KEGG
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AffyNet
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PC sid
UniChem
Patents
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PubMed
| 416 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090946
(CHEMBL3582010)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)NCCF Show InChI InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18?,19?,20-,22?,23+,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 421 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090960
(CHEMBL3582015)Show SMILES COC1CN(C1)c1ccc(nc1OCC1CC1)C(=O)NC(C)(C)Cc1nnc(o1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H30FN5O4/c1-26(2,12-22-30-31-24(36-22)17-6-8-18(27)9-7-17)29-23(33)20-10-11-21(32-13-19(14-32)34-3)25(28-20)35-15-16-4-5-16/h6-11,16,19H,4-5,12-15H2,1-3H3,(H,29,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 466 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090960
(CHEMBL3582015)Show SMILES COC1CN(C1)c1ccc(nc1OCC1CC1)C(=O)NC(C)(C)Cc1nnc(o1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H30FN5O4/c1-26(2,12-22-30-31-24(36-22)17-6-8-18(27)9-7-17)29-23(33)20-10-11-21(32-13-19(14-32)34-3)25(28-20)35-15-16-4-5-16/h6-11,16,19H,4-5,12-15H2,1-3H3,(H,29,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 504 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50072353
(CHEMBL3409317)Show InChI InChI=1S/C18H23FN2O3/c1-18(2,3)20-17(23)13-11-21(10-6-9-19)15-12(16(13)22)7-5-8-14(15)24-4/h5,7-8,11H,6,9-10H2,1-4H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor transfected in CHOK1 cells after 90 mins by liquid scintillation counting analysis |
Eur J Med Chem 92: 554-64 (2015)
Article DOI: 10.1016/j.ejmech.2015.01.028
BindingDB Entry DOI: 10.7270/Q2BP04H0 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090964
(CHEMBL3582019)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NCCF Show InChI InChI=1S/C21H29F3N4O3/c1-3-20(4-2,19(30)25-10-9-22)27-17(29)15-7-8-16(28-12-21(23,24)13-28)18(26-15)31-11-14-5-6-14/h7-8,14H,3-6,9-13H2,1-2H3,(H,25,30)(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 774 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090946
(CHEMBL3582010)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)NCCF Show InChI InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18?,19?,20-,22?,23+,24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 902 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090923
(CHEMBL3582013)Show SMILES COC1CN(C1)c1ccc(nc1OCC1CC1)C(=O)NC1(CC(N)=O)COC1 Show InChI InChI=1S/C19H26N4O5/c1-26-13-7-23(8-13)15-5-4-14(21-18(15)28-9-12-2-3-12)17(25)22-19(6-16(20)24)10-27-11-19/h4-5,12-13H,2-3,6-11H2,1H3,(H2,20,24)(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090959
(CHEMBL3582021)Show SMILES CC(C)(Cc1nnc(o1)-c1ccc(F)cc1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 Show InChI InChI=1S/C25H26F3N5O3/c1-24(2,11-20-31-32-22(36-20)16-5-7-17(26)8-6-16)30-21(34)18-9-10-19(33-13-25(27,28)14-33)23(29-18)35-12-15-3-4-15/h5-10,15H,3-4,11-14H2,1-2H3,(H,30,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig)) | BDBM50441935
(CHEMBL2437385)Show SMILES COc1cccc2CCN(CCCN3CCc4cc(OC)c(OC)cc4C3)C(=O)c12 Show InChI InChI=1S/C24H30N2O4/c1-28-20-7-4-6-17-9-13-26(24(27)23(17)20)11-5-10-25-12-8-18-14-21(29-2)22(30-3)15-19(18)16-25/h4,6-7,14-15H,5,8-13,16H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari ALDO MORO
Curated by ChEMBL
| Assay Description
Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in Dunkin guinea pig brain membranes without cerebellum |
Eur J Med Chem 69: 920-30 (2013)
Article DOI: 10.1016/j.ejmech.2013.09.018
BindingDB Entry DOI: 10.7270/Q2K64KH7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50090958
(CHEMBL3582011)Show SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OC)c(OCC2CC2)n1)C(=O)NCCCF Show InChI InChI=1S/C23H35FN4O4/c1-4-23(5-2,22(30)25-12-6-11-24)27-20(29)18-9-10-19(28-13-17(14-28)31-3)21(26-18)32-15-16-7-8-16/h9-10,16-17H,4-8,11-15H2,1-3H3,(H,25,30)(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090961
(CHEMBL3582016)Show SMILES COC1CN(C1)c1ccc(nc1OCC1CC1)C(=O)NCC1(O)CCCCC1 Show InChI InChI=1S/C21H31N3O4/c1-27-16-11-24(12-16)18-8-7-17(23-20(18)28-13-15-5-6-15)19(25)22-14-21(26)9-3-2-4-10-21/h7-8,15-16,26H,2-6,9-14H2,1H3,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50090938
(CHEMBL3582014)Show SMILES COC1CN(C1)c1ccc(nc1OCC1CC1)C(=O)OC(C)(C)c1cc(N)on1 Show InChI InChI=1S/C20H26N4O5/c1-20(2,16-8-17(21)29-23-16)28-19(25)14-6-7-15(24-9-13(10-24)26-3)18(22-14)27-11-12-4-5-12/h6-8,12-13H,4-5,9-11,21H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in CHO cell membranes |
J Med Chem 58: 4266-77 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00283
BindingDB Entry DOI: 10.7270/Q2542QBG |
More data for this
Ligand-Target Pair | |
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