| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK1 |
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| Ligand | BDBM50443940 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1278068 (CHEMBL3095419) |
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| IC50 | >10000±n/a nM |
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| Citation |  Deau, E; Loidreau, Y; Marchand, P; Nourrisson, MR; Loaëc, N; Meijer, L; Levacher, V; Besson, T Synthesis of novel 7-substituted pyrido[2',3':4,5]furo[3,2-d]pyrimidin-4-amines and their N-aryl analogues and evaluation of their inhibitory activity against Ser/Thr kinases. Bioorg Med Chem Lett23:6784-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK1 |
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| Name: | Dual specificity protein kinase CLK1 |
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| Synonyms: | CDC-like kinase 1 | CDC-like kinase 1 (CLK1) | CDC2-like kinase 1 (CLK1) | CLK | CLK1 | CLK1_HUMAN | Dual specificity protein kinase CLK1 | Dual specificity protein kinase CLK1/CLK4 | Dual specificty protein kinase CLK1 |
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| Type: | Protein |
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| Mol. Mass.: | 57322.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49759 |
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| Residue: | 484 |
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| Sequence: | MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESR
SINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIH
HSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECID
HKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIV
FELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSD
YTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPC
DVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWD
EHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLL
KKSI
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| BDBM50443940 |
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| n/a |
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| Name | BDBM50443940 |
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| Synonyms: | CHEMBL3091816 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8BrFN4O |
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| Mol. Mass. | 359.153 |
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| SMILES | Fc1cc(Br)ccc1Nc1ncnc2c1oc1cccnc21 |
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| Structure | 
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