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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase receptor UFO | ||
| Ligand | BDBM50444255 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1277931 (CHEMBL3094775) | ||
| IC50 | >30000±n/a nM | ||
| Citation |  Zhang, W; McIver, AL; Stashko, MA; DeRyckere, D; Branchford, BR; Hunter, D; Kireev, D; Miley, MJ; Norris-Drouin, J; Stewart, WM; Lee, M; Sather, S; Zhou, Y; Di Paola, JA; Machius, M; Janzen, WP; Earp, HS; Graham, DK; Frye, SV; Wang, X Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis. J Med Chem56:9693-700 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase receptor UFO | |||
| Name: | Tyrosine-protein kinase receptor UFO | ||
| Synonyms: | AXL | AXL oncogene | TEL/AXL | Tyrosine-protein kinase receptor UFO (AXL) | UFO | UFO_HUMAN | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 98316.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P30530 | ||
| Residue: | 894 | ||
| Sequence: |
| ||
| BDBM50444255 | |||
| n/a | |||
| Name | BDBM50444255 | ||
| Synonyms: | CHEMBL3093762 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H34N6O2 | ||
| Mol. Mass. | 390.523 | ||
| SMILES | CCCCNc1ncc(C(=O)N2CCC(N)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:20.20,wD:23.24,(54.73,-23.53,;56.06,-22.76,;57.39,-23.53,;58.73,-22.76,;60.06,-23.53,;61.4,-22.76,;62.73,-23.53,;64.07,-22.76,;64.06,-21.21,;65.39,-20.43,;65.39,-18.89,;66.73,-21.2,;66.73,-22.73,;68.06,-23.5,;69.39,-22.73,;70.73,-23.5,;69.39,-21.19,;68.05,-20.42,;62.73,-20.45,;62.72,-18.91,;61.39,-18.14,;60.05,-18.92,;58.72,-18.15,;58.71,-16.6,;57.38,-15.83,;60.05,-15.84,;61.38,-16.6,;61.4,-21.22,)| | ||
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