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TargetSuppressor of tumorigenicity 14 protein
LigandBDBM50038002
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1281386 (CHEMBL3101481)
Ki 400000±n/a nM
Citation Goswami, RMukherjee, SWohlfahrt, GGhadiyaram, CNagaraj, JChandra, BRSistla, RKSatyam, LKSamiulla, DSMoilanen, ASubramanya, HSRamachandra, M Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors. ACS Med Chem Lett4:1152-7 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Suppressor of tumorigenicity 14 protein
Name:Suppressor of tumorigenicity 14 protein
Synonyms:Epithin | Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein | MT-SP1 | Membrane-type serine protease 1 | PRSS14 | Prostamin | SNC19 | ST14 | ST14_HUMAN | Serine protease TADG-15 | Suppressor of tumorigenicity 14 protein | Suppressor of tumorigenicity protein 14 | TADG15
Type:Single-pass type II membrane protein
Mol. Mass.:94769.23
Organism:Homo sapiens (Human)
Description:Q9Y5Y6
Residue:855
Sequence:
MGSDRARKGGGGPKDFGAGLKYNSRHEKVNGLEEGVEFLPVNNVKKVEKHGPGRWVVLAA
VLIGLLLVLLGIGFLVWHLQYRDVRVQKVFNGYMRITNENFVDAYENSNSTEFVSLASKV
KDALKLLYSGVPFLGPYHKESAVTAFSEGSVIAYYWSEFSIPQHLVEEAERVMAEERVVM
LPPRARSLKSFVVTSVVAFPTDSKTVQRTQDNSCSFGLHARGVELMRFTTPGFPDSPYPA
HARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHALVQLCGTYPPS
YNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQGTFNSPYYPGHY
PPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEINGEKYCGERSQFVVTS
NSNKITVRFHSDQSYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDH
SDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSK
SQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNGLCLSKGNPECDGKEDCSDGSDEK
DCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYID
DRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKP
AEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLL
PQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYT
RLPLFRDWIKENTGV
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  Blast E-value cutoff:
BDBM50038002
n/a
NameBDBM50038002
Synonyms:Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537204 | benzamidine
TypeSmall organic molecule
Emp. Form.C7H8N2
Mol. Mass.120.1518
SMILESNC(=N)c1ccccc1
Structure
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