| Reaction Details |
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 | Report a problem with these data |
| Target | Lethal factor |
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| Ligand | BDBM50444728 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1281780 (CHEMBL3100683) |
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| Ki | 478±n/a nM |
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| Citation |  Williams, JD; Khan, AR; Cardinale, SC; Butler, MM; Bowlin, TL; Peet, NP Small molecule inhibitors of anthrax lethal factor toxin. Bioorg Med Chem22:419-34 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lethal factor |
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| Name: | Lethal factor |
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| Synonyms: | Anthrax Lethal Factor (LF) | Anthrax lethal factor | Antrax lethal toxin | LEF_BACAN | lef | lethal factor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93758.56 |
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| Organism: | Bacillus anthracis |
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| Description: | ChEMBL_1460338 |
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| Residue: | 809 |
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| Sequence: | MNIKKEFIKVISMSCLVTAITLSGPVFIPLVQGAGGHGDVGMHVKEKEKNKDENKRKDEE
RNKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAEKLLEKVPSDVLEMYKAIGGKIYIVDGD
ITKHISLEALSEDKKKIKDIYGKDALLHEHYVYAKEGYEPVLVIQSSEDYVENTEKALNV
YYEIGKILSRDILSKINQPYQKFLDVLNTIKNASDSDGQDLLFTNQLKEHPTDFSVEFLE
QNSNEVQEVFAKAFAYYIEPQHRDVLQLYAPEAFNYMDKFNEQEINLSLEELKDQRMLAR
YEKWEKIKQHYQHWSDSLSEEGRGLLKKLQIPIEPKKDDIIHSLSQEEKELLKRIQIDSS
DFLSTEEKEFLKKLQIDIRDSLSEEEKELLNRIQVDSSNPLSEKEKEFLKKLKLDIQPYD
INQRLQDTGGLIDSPSINLDVRKQYKRDIQNIDALLHQSIGSTLYNKIYLYENMNINNLT
ATLGADLVDSTDNTKINRGIFNEFKKNFKYSISSNYMIVDINERPALDNERLKWRIQLSP
DTRAGYLENGKLILQRNIGLEIKDVQIIKQSEKEYIRIDAKVVPKSKIDTKIQEAQLNIN
QEWNKALGLPKYTKLITFNVHNRYASNIVESAYLILNEWKNNIQSDLIKKVTNYLVDGNG
RFVFTDITLPNIAEQYTHQDEIYEQVHSKGLYVPESRSILLHGPSKGVELRNDSEGFIHE
FGHAVDDYAGYLLDKNQSDLVTNSKKFIDIFKEEGSNLTSYGRTNEAEFFAEAFRLMHST
DHAERLKVQKNAPKTFQFINDQIKFIINS
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| BDBM50444728 |
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| n/a |
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| Name | BDBM50444728 |
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| Synonyms: | CHEMBL3098990 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O2 |
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| Mol. Mass. | 335.3996 |
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| SMILES | COc1ccccc1CCC(=O)Nc1ccc2nc(C)cc(N)c2c1 |
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| Structure | 
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