| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
|---|
| Ligand | BDBM50445985 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1283539 (CHEMBL3107470) |
|---|
| IC50 | 112530±n/a nM |
|---|
| Citation |  Khan, MS; Munawar, MA; Ashraf, M; Alam, U; Ata, A; Asiri, AM; Kousar, S; Khan, MA Synthesis of novel indenoquinoxaline derivatives as potenta-glucosidase inhibitors. Bioorg Med Chem22:1195-200 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oligo-1,6-glucosidase IMA1 |
|---|
| Name: | Oligo-1,6-glucosidase IMA1 |
|---|
| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68577.59 |
|---|
| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
|---|
| Description: | n/a |
|---|
| Residue: | 589 |
|---|
| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
|
|
|
|---|
| BDBM50445985 |
|---|
| n/a |
|---|
| Name | BDBM50445985 |
|---|
| Synonyms: | CHEMBL3103157 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H13BrN4O |
|---|
| Mol. Mass. | 429.269 |
|---|
| SMILES | Brc1cccc(c1)C(=O)N=Nc1c2ccccc2c2nc3ccccc3[nH]c12 |w:10.11| |
|---|
| Structure | 
|
|---|
Search and Browse
